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Should I not get a puppy from this litter due to the mom’s genetic results?

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dcm
1K views 2 replies 3 participants last post by  Gretchen_Red 
#1 · (Edited)
#2 · (Edited)
As far as cardio goes, what you really need to see is good results on a cardiogram and a 24 hour holter, on both the dam and the sire, done within the last year, or ideally within 6 months of the breeding. You should also look at the bloodlines--near ancestors, siblings of the parents, and pups from a previous breeding of either parent--to see if there is DCM or early death recorded.

The DCM genetic testing (DCM 1 and DCM 2) is mostly of academic interest--dogs can be positive for one or both genes and never develop DCM, and dogs can be negative for both and go on to develop DCM. The disease is apparently the result of multiple genes acting together, and research is just beginning to sort it out.

A cardiogram and a 24-hour holter is the best way we have to monitor our dogs DCM status.

Do you know the sire's vWD results? If the sire is clear, the pups will not develop the disease--carriers (one good gene and one bad gene) don't show symptoms, and some of the pups can be completely clear. If the sire is a carrier, there is a 25% chance the pup will be vWD genetically affected (two bad genes--which actually may not result in a major bleeding problem.) If the sire is genetically affected (2 bad genes) bred to a carrier mom, 50% of the pups may be vWD affected. Of course, these are averages--individual litters may not reflect those percentages.

If it is possible a puppy might be genetically affected according to his parents' vWD status, the breeder can always do a genetic test on each puppy so buyers can be forewarned if there is a problem with a particular puppy and choose whether he wants to go through with the purchase.
 
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