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My dog Bella suffers from pretty severe car sickness and resulting car anxiety. We've taken her to our dog park many, many times and pretty much take her with us whenever we go hiking or running so she knows she's going somewhere really fun. But those many short rides did nothing to fix her car sickness. And we've tried Dramamine, Benadryl, not feeding her beforehand, Gingersnaps, etc, but none of that stuff worked. I was about to buy a Thundershirt and even spoke with our vet about possible anti-anxiety medications or reside to only taking her out when absolutely necessary. She simply prescribed us "Bonine" and said dogs had more luck with it. So I promptly bought some and gave her a pill before our trip to the dog park today. Lo & behold, she was like a different dog and actually seemed to enjoy the car ride and was able to sit up and look out the window. My husband and I were so thrilled and relieved we actually enjoyed the car ride, too. Feeling so happy! Hope the stuff keeps on working 