I have an 8 year old dobe that just was breed today by my 1 year old dobe. The problem is my girl has very Heath issue in the book (thyroid, liver, DCM and is vWD affected). I am waiting on progesterone results. But if she did get breed I need to research options to terminate as it will be bad for her health and not a responsible breeder to have puppies that could have her health problems. I know there was an estrogen shot that could be used but it has may side effects as spaying her is nor an option with her health. Has anyone had experience with alizin? If so was it used on a healthy dog? What issues/side effects did you have?