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Sometimes normal values are lab dependent--that is, different labs may have a different range of normal values depending on the methods they use and the population they typically test (young vs old, for example).
In people, the ranges are quite different depending on their ages--ALP [alkaline phosphatase] can be increased with both various liver disorders and with actively growing bone tissue, so it will be higher during times of active growth (growth spurts in kids, pregnant women.)
An increased alk phos in dogs does not always indicate liver problems. From "Diagnostic approach in dogs with increased ALP activity"
"Causes of increased total ALP activity can be classified as: 1). Age (young dogs) and breed-related considerations (Siberian Huskies with familial hyperphosphatasemia; Scottish Terriers); 2) Drug-induced (corticosteroids, phenobarbital, others); 3) Cushing's Disease; 4) Primary hepatobiliary disease (intra- and extrahepatic cholestatic disorders, including vacuolar hepatopathy, cholangitis, hepatitis, neoplasia, nodular hyperplasia); 5) Systemic disorders causing reactive hepatopathy or physiologic stress associated with acute or chronic illness (neoplasia, infection/inflammation; pancreatitis; GI disease; endocrine disorders such as diabetes mellitus, hypothyroidism) and 6) Bone-related disorders (neoplasia, nutritional osteopathy, hyperparathyroidism)"
All of this gobbledy gook basically means that Alk Phos is good for picking up liver disorders, but an increased level may not specifically point to liver problems.
ALT is mostly specific for the liver though, and his value for that is increased also....
Last edited by melbrod; 06-04-2020 at 10:07 AM.