Originally Posted by Kathryn Durrant View Post
Thanks for your reply. I have read a lot online and am struggling to find and alternative option. Any advice would be gratefully received.
Has anyone had experience of these side effects? Or know of any long term complications?
I don't know if you have had your puppy seen by a vet internist but I'd do that before I'd put a Dobe on a sulfonamide.
I can tell you all about sulfonamide reactiona in people (it's a common drug allergy)--and I am wildly allergic to all sulfonamides not just the potentiated sulfonamides (Sulfatrim is a potentiated sulfonamide)--and I've had Dobes since 1959 and the only sulfonamide any Dobe of mine has been medicated with is Albon (this contains a sulfonamide radical but rarely causes any kind of reaction.)
Have they run a culture and sensativity test to see what drugs this salmonella is actually affected by? If not I'd certainly want that before I'd go for Sulfatrim as a last resort.
Doberman's as you've found from your reading are a breed that is noticeably more likely to react to sulfa drugs. For me the first reaction is hives and that is almost instant--the last time a doctor missed the information in my medical file that clearly says no sulfonamides and prescribed them--and I didn't notice (not paying sufficient attention to labels) what had been prescribed--I took one tablet and before I even finished drinking the glass of water I had a full batch of hives starting at my scalp and working it's way down my body. Reactions can vary (for people and Dobes) but the severe ones can kill a dog--the drug will cause an anaphylactic shock reaction.
Not all Dobermans react to sulfonamids but enough do that when antibiotics were fairly new and the sulfonamides were much more widely used it turned out that a whole lot of people and several specific breeds of dogs were reactive to all sulfonamides but the potentiated sulfonamides like Sulfatrim were much more likely to create the reactions. And that's the reason that the medical recommendations are to NOT use them on Dobermans.
Today--there are many new antibiotics that can be used instead of a sulfonamide. That's why they should have (or should if they haven't already) run a culture and sensitivity.
It's really unfortunate that for a few things (and I wasn't aware that salmonella was one of them) the sulfonamides are the most effective treatment (to say nothing of being one of the least expensive).
I wish you the best of luck on this. Please let us know what you decide to do and what works--it helps to be able to pass this information on when the question comes up (and the sulfonamide question comes up fairly often).