sebaceous adenitis in the Dobe? - Doberman Forum : Doberman Breed Dog Forums
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post #1 of 11 (permalink) Old 06-09-2016, 01:09 PM Thread Starter
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sebaceous adenitis in the Dobe?

Hy Everyone....

Im absolutly defistated at the moment... i got this diagnosis today on my "Breeding" female needless to say i have taken her out of my breeding programm and that she cant be missused she will stay with me untill her last day on earth.

Have you ever heard of this on a Doberman? Its usually an Akita or Poodle thing as fahr as i have reasearched. Its making me absolutly nuts since it cant be cured....

She is thankfully not in pain... she has no itching going on, but needing to bathe her so often and oil her and bathe her again is it really an option? It will inflame again and that for the rest of her life... no medication can help exept when i gets really bad Antibiothics...

Has anyone got more information on this does anyone know how else i can help my poor baby girl?

Quote:
Sebaceous adenitis is an autoimmune, inflammatory, skin disease of currently unknown cause. Research is currently underway to find if there is a genetic predisposition for SA, and the exact mode of inheritance remains unknown. However, it is postulated that it is an autosomal recessive acquired condition. It has no sex-predisposition. There are two expressions of this condition, one for long or double coated breeds and one for short coated breeds, both with differing presentations.

For long- or double-coated breeds such as Poodles, Akitas and Samoyeds, the condition often presents itself with silvery dandruff which adheres to the coat, hair loss (not to be confused with moulting or "blowing coat"), a dull and brittle coat, and later on skin lesions along the back and ears as well as thickened skin and a musty or rancid odour. For short-coated breeds such as Vizslas, the condition causes facial swellings, nodular skin lesions, fine dandruff which does not adhere to the coat, and a general "moth-eaten" appearance to the coat.
Quote:
Treatment
There is no cure for this condition.[citation needed] Treatment is generally lifelong and takes the form of bathing and soaking in mineral oils and washing with antibiotic shampoos to try to alleviate symptoms and slow the condition's progression. Antiseptic and antibiotic shampoos (chlorhexidine or benzoyl peroxide) are used to manage further secondary bacterial infection. For some breeds, cyclosporine or corticosteroids and immunosuppressant drugs may be effective, and it is postulated, through some studies, that large doses of vitamin A given orally may result in some improvement.

It has been suggested in the paper by Angus (2009) that the more aggressively one applies the topical methods of treatment, the less aggressively one needs to employ the immunosuppressant therapy. The suggestion is that this phenomenon may be due to a cyclic feedback whereby secondary infection, when not aggressively treated with topical therapy, increases and contributes to further sebaceous gland inflammation.

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post #2 of 11 (permalink) Old 06-09-2016, 01:19 PM
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Thank you for sharing and thank you for taking your bitch out of breeding. I understand how you could be devastated, I would be too.

What symptoms was she showing that made you take her to get looked at?
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post #3 of 11 (permalink) Old 06-09-2016, 01:40 PM Thread Starter
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First it was just loss of hair and a bit of dandruff... nothing in perticular actaually but i worry fast when something is wrong with the Fur of my dogs...

My Vet thought first of all Demodex... so we got skinn and it wasnt that so we kept searching blood tests and the whole testing process, while waiting on the result it got worse and worse each day.... then she got thick parts on the ears so we thought a ear necrosis tested on that gave her oil baths but nothing helped... again tests and i changed her diet completly as we also thought on food alergy...

Nothing came back... then she started getting kind of like hot spots on the chest... they grew bigger and bigger and i gently scroked over them and it burst open... blood some puff and tallow... okay unusiual so i called the Vet and we drove imidiatly to her... she said its doberman untypical but she has seen it on a Wisler and Akita and she wants to test something but is not telling me because im a bit low on nerves at the moment because of my baby... so we waited and it got worse again unill i got back results today... my Vet cryed with me on the phone...
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post #4 of 11 (permalink) Old 06-09-2016, 02:06 PM
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So sorry to read about this Dobermans4life--I thought that SA in Poodles had a genetic test but from what I read in your post I must be wrong. Time to go do some research.

I've never heard of this in Dobermans and I've been in the breed a long, long time so it must be quite uncommon.
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post #5 of 11 (permalink) Old 06-09-2016, 02:09 PM Thread Starter
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Quote:
Originally Posted by dobebug View Post
So sorry to read about this Dobermans4life--I thought that SA in Poodles had a genetic test but from what I read in your post I must be wrong. Time to go do some research.

I've never heard of this in Dobermans and I've been in the breed a long, long time so it must be quite uncommon.
My Vet thinks Era is one of the first, she knows of one more in Serbia (where my girl comes from)

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post #6 of 11 (permalink) Old 06-09-2016, 03:31 PM
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Another thought is to see a Vet Dermatologist. It must be hard to see this on your fur baby.
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post #7 of 11 (permalink) Old 06-09-2016, 08:48 PM
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I went looking for anything about a genetic test for SA--couldn't find anything--must have made it up out of whole cloth or had a nightmare or something...

Sometimes very uncommon stuff shows up in population groups that are somewhat isolated. Interesting that your vet has only seen it in one Serbian dobe and heard of it in only one other Serbian dobe.

Again--I'm so sorry you and your bitch have to go through this...

I know that the Standard Poodle breeders have known about SA for a long time and are thoroughly convinced that it is genetic and the good breeders ALWAYS withdraw any dog with a definite dx of SA from the breeding pool.
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post #8 of 11 (permalink) Old 06-10-2016, 04:30 AM Thread Starter
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Thank you dobebug for trying to find something, i have taken er out of my breeding program and i have informed both breeders of the sickness of my girl, my breeder i got the puppy from was devistated and the other (a pritty big breeder) didnt answer to me (why should he those big breeders brush it off)

Im a little breeder i only had this one female to start off, its going to take me a while to save up and if i ever get that quality of a female again als little breeder in my hands i doubt it... i will have to start from scratch but i dont mind its just gona take me a while to save up since that testing ate all my reservs but maybe its a good thing, her line had pritty much DCM in it and i will do even more research to get a Female with much less DCM in the line to have a better base to start with...

My Female is going to stay with me, since if i sell her i canot be certain she will not be used to breed and i think our lovley breed has enouph troubles withought this aswell.

Wish me luck on getting my baby somewhat okay again and on finding a new female any tipps in Europe welcome just ind of lost at the moment.

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post #9 of 11 (permalink) Old 06-17-2016, 07:32 AM Thread Starter
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UPDATE:

Im going nuts here everyone.... i just got a call that the stuff we sent in was kontaminated with white hair of god knows what!!!

This means the diagnosis is WRONG and we have to start from the beginning.... all testing is going to start over as soon as the wounds from last time healed up.

Please Please keep your fingers crossed for us that she doesnt have anything really bad and can be healed.

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post #10 of 11 (permalink) Old 06-17-2016, 12:02 PM
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Fingers crossed and good thoughts sent--are the tests from punch biopsies?
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post #11 of 11 (permalink) Old 06-17-2016, 12:18 PM Thread Starter
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Quote:
Originally Posted by dobebug View Post
Fingers crossed and good thoughts sent--are the tests from punch biopsies?
Yes 6x on different places

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