I recommend Frontline - much safer. The only species that seems to have a problem with it is rabbits. Most OTC tick products contain permethrins (organophosphate) which are effective, but have an increased risk of side effects (for ANY breed). As for their mosquito repellency..... it's a lot like our mosquito repellents or horse fly sprays.... have you ever had one that lasted anywhere near how long it says??? Most horse fly sprays have permethrins and are labeled to last "up to 7 days" or "up to 14 days" - RIGHT

I have yet to see one of these that you don't need to reapply at least every other day. Permethrins are very toxic to cats, so if you have cats I would not recommend it (also should be cautious around small children). On a side note, most of the client dogs I've had come in who are using an OTC tick product (such as Hartz) have a greasy streak down their back for weeks. I have asked multiple owners if they just applied the tick preventative and all have said "oh, no we put that on last week (or a couple weeks ago or whatever)". Some of the OTC products are also less waterproof.
Checking your dog over carefully after they've been somewhere where's there are ticks and removing them right away can also help prevent tick-borne disease (lyme, Ehrlichia, Anaplasma, etc).